Global Research in Paediatrics

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About Global Research in Paediatrics

Global Research in Paediatrics – Network of Excellence (GRiP) is an EU-funded project, which aims to stimulate and facilitate the development and safe use of medicines in children.


The main reason for the existence of GRiP is the lack of appropriate testing of paediatric drugs, with most drugs having inadequate information about dosing regimen, dose adjustment and administration. GRiP partners are working to build and maintain an infrastructure matrix, which has the core aim of reducing the current fragmentation of the efforts to study and develop the use of medicine in children. GRiP will mobilize 21 partners from Europe, North America and Japan, as well as the WHO. By linking the existing paediatric research networks, GRIP will involve more than 1000 institutions worldwide.


This website is the main communication tool for GRiP, it is constantly updated to provide quality information on the efforts of GRiP members in the field of paediatric clinical pharmacology


Browse this section for information on: 


GRiP Partners and funding

• GRiP Newsletters

• GRiP Blog

• GRiP communication products


See the Objectives and results section of the website for a detailed account of present, past and future GRiP activities. 

For a quick, up-to-date summary of all the results that GRiP has shown so far, please visit the Results Summary page.


If you wish to contact GRiP management, please see the contacts page - Contact GRiP 



Global Research in Paediatrics in a nutshell


The main characteristics of GRiP, as a project for the improvement of paediatric health, are:


1. GRiP is data driven and the data and evidence provide the basis, authority and responsibility to our efforts. The basis is the scientific method, the authority is based on the principle of data driven and evidence based and the responsibility is that we have the obligation to share the data to advance the field.


2. GRiP is transparent through a state of the art consensus driven process that by intent is inclusive of stakeholders.


3. GRiP is relevant because GRiP is dedicated to developing tools and methods to catalyse research, improve and sustain quality, lower costs and harmonize training and practice.


4. GRiP, through the mission and process, can begin to reach out to specific future partners such as the pharmaceutical industry, funding organizations, patient and advocate organizations and regulators on a flow basis as deliverables are completed.


5. GRiP priorities are to coordinate the completion of deliverables, affirm the utility of deliverables and develop sustainable models to maintain the utility and relevance of the Work Package products.


The GRiP infrastructure matrix


The GRiP infrastructure matrix will promote the sharing of best practices, strategies and plans. Key to these efforts will unifying evaluating methodologies, research standardised recommendations. GRiP intends to produce guidelines which will reflect the needs of researchers (including industry) and patients facilitate interoperability in paediatric research and will improve efficiency in clinical research and enable comparison of study results. New protocol designs, procedures and methodologies for clinical trials in children will also be explored and validated to fill the important ‘gaps’ that currently exist in paediatric medicine.


GRiP Educational Programme


Paediatric studies requires well trained researchers, investigators and other experts in number and capacity that currently do not exist.

Since the project aims to reduce fragmentation, the key component of GRiP will be the development and implementation of a Joint Paediatric Clinical Pharmacology Training Program in collaboration with International stakeholders. 


This training regimen will build on the existing experience and capacity of industry leaders and will aim to prepare experts in paediatric clinical pharmacology able to work both at regulatory and clinical research level. The program will be coordinated by experienced educators from Europe, North America and Japan, and be delivered by a broad range of experts in each field.


The Objectives and results section of the website sheds more light on the structure, the objectives and the output of the GRiP Project.